Daivobet

1 tube 60 g pomade or gel
Active ingredients: Calcipotriol and betamethasone
Daivobet 50 micrograms / g + 0.5 mg / g ointment
Calcipotriol / betamethasone

What is it and what is it used for?

Daivobet is used for topical treatment of psoriasis (psoriasis) of the scalp as well as on the skin of other parts of the body to treat mild to moderate plaque psoriasis (psoriasis vulgaris) in adults. Psoriasis is caused when skin cells are formed too quickly. This causes redness, scaling and thickening of the skin.
Daivobet contains calcipotriol and betamethasone. Use of calcipotriol can normalize the growth of skin cells. Betamethasone inhibits inflammation.

What you need to consider before using it?

Daivobet must not be used,
if you are hypersensitive (allergic) to calcipotriol, betamethasone or any of the other ingredients of Daivobet
if you have problems with your calcium levels (talk to your doctor)
if you suffer from the following forms of psoriasis: erythrodermic and pustular psoriasis exfoliative and (talk to your doctor)
As Daivobet contains a strong steroid, it should NOT be applied to skin areas that are affected by the following infections or diseases:
Infections caused by viruses (eg. As cold sores or chicken pox)
Infections caused by fungi (eg. As athlete's foot or ringworm)
Infections caused by bacteria
Infections caused by parasites (eg. As scabies)
Tuberculosis (TB) or syphilis
perioral dermatitis (rash with redness of the skin around the mouth)
thin skin, easily damaged skin vessels, stretch marks
Ichthyosis (dry skin with fish scales)
Acne (pimples)
Rosacea (strong feeling of warmth in the face and strong facial flushing)
Sores or cracked skin
Itching of the anus (back) or genitals (sex organs).

Take special care with the use of Daivobet gel is required
If you are taking other medicines that contain a corticosteroid, as it may cause side effects.
If you use this medicine for a long time and want to exit the application (if steroids are discontinued abruptly, there is a danger that the psoriasis worsens or again 'flares').
If you have diabetes mellitus (diabetes) as the steroid may affect your blood sugar levels.
If your skin inflamed, because the treatment must be discontinued under certain circumstances.
If you suffer from a certain type of psoriasis, psoriasis guttata is called.
If you have a serious liver or kidney disease.

Special precautions
Avoid treating more than 30% of your body surface area and do not use more than 15 grams per day.
Use Daivobet not as this will increase under a bathing cap, under bandages or dressings, the absorption of the steroid in the body.
Avoid applying over large areas of damaged skin or skin folds (groin, armpits or under the breast) as it increases the absorption of the steroid in the body.
Avoid applying on the face or genitals (sex organs) as they are very sensitive to steroids.
Avoid excessive sunbathing, excessive use of tanning beds and other forms of light treatment.
The use of Daivobet may in doping controls lead to positive results.

Children and adolescents
Daivobet is not recommended for use in children under 18 years.
In application of Daivobet with other medicinal products
Please inform your doctor or pharmacist if you are taking other medicines / or have recently taken / used, even if it is not prescribed.

pregnancy and breast feeding period
You may Daivobet if you are pregnant (or might be pregnant) or breastfeeding, only use it if your medical practitioner deems appropriate. If your doctor has allowed you to breastfeed, be careful with the use of Daivobet and do not wear it on the chest.
Ask. Before taking any medicine your doctor or pharmacist for advice
Driving and using machines
This medicine should not affect the ability to drive and use machines.

Important information about some of the ingredients of Daivobet
Daivobet contains butylhydroxytoluene (E321) which may cause, irritation of the eyes and mucous membranes local skin reactions (eg contact dermatitis. B.).

How is it used?

Apply Daivobet exactly as your doctor has told you to. You should check with your doctor or pharmacist if you are unsure.
As Daivobet apply? Daivobet is applied to the skin.

Instructions for the correct application
Apply Daivobet only on the affected skin and not on other parts of the skin that are not affected by the psoriasis.
Enter Daivobet on a clean finger or directly onto the skin area affected by psoriasis.
Wear Daivobet with the fingertips to the affected areas and massage Daivobet while gently until the affected by psoriasis bodies are covered by a thin layer of pomade.
Do not connect the treated area, covering fixed or wrap.
Wash your hands after the application of Daivobet hands thoroughly. This can be avoided that Pomade inadvertently to other parts of the body unit (especially the face, mouth and eyes).
It does not matter if some pomade gets accidentally hit the non-diseased skin around the affected skin around. You should wipe the pomade but when it is spread over a large area to non-diseased skin.
To achieve an optimal effect it is recommended not to take a shower immediately after application of Daivobet or bathe.
Avoid the application of pomade contact with materials on which can easily lead to fat stains (eg. As silk).

Duration of treatment
Apply Daivobet once daily. It is more convenient to use the ointment in the evening.
Your doctor may determine a different treatment period.
Your doctor may determine retreatment.
Apply no more than 15 grams in one day
If you are taking other preparations containing calcipotriol, the total amount should be no more than 15 grams per day of calcipotriol containing products. A total of not more than 30% of the body surface to be treated.

If you use a larger amount of Daivobet than you should
Consult your doctor if you use more than 15 grams in one day.
The use of excessive quantities of Daivobet over a prolonged period can lead to increased calcium in the blood, which usually normalises when discontinuing treatment.
Your doctor may need to do blood tests to ensure that the application of large quantities of the gel has not led to such a problem.
The use of excessive quantities of Daivobet over a long period can also cause your adrenal glands (located near the kidneys and hormones form) no longer work properly.

If you forget to use Daivobet gel
Apply. Not take a double dose if you have forgotten dose
If you stop using Daivobet gel
The use of Daivobet should be stopped in accordance with the doctor's prescription. You must Daivobet, especially after prolonged use, settle gradually under certain circumstances.
If you have any further questions on the use of this product, ask your doctor or pharmacist.

What are possible side effects?

Like all medicines, Daivobet can cause side effects, although not everybody gets them.
In about 1 in 12 patients experience side effects. Most side effects are reactions at the site at which the gel has been applied.
Serious side effects:
Immediately inform or as soon as possible with your doctor / nurse if any of the following side effects you are experiencing. Treatment should be discontinued under certain circumstances:
The following serious adverse reactions have been reported for Daivobet:
Uncommon (affects less than 1 in 100):
Worsening of your psoriasis. If deteriorates your psoriasis, tell your doctor as soon as possible.
From some serious side effects, we know that they betamethasone (a strong steroid), one of the ingredients of Daivobet, caused. You should inform your doctor as soon as possible if any of these serious side effects you are experiencing. These side effects occur primarily under long-term use or use under tight fitting associations.
These side effects include:
The adrenal glands are not working properly. Signs are fatigue, depression (depression) and anxiety.
Cataracts (signs are veil and blurred vision, decreased vision in the dark and light sensitivity) or elevated intraocular pressure (signs are eye pain, eye redness, decreased vision or blurred vision).
Infections (because your immune system is, the fights infections, suppressed or weakened).
Pustular psoriasis (reddened skin area with yellowish pustules usually on the hands and feet). If you notice this, stop taking Daivobet and talk as soon as possible with your doctor.
Affect the diabetic metabolism (if you have diabetes [diabetes], can fluctuations in your blood sugar levels occur).
Serious side effects caused by calcipotriol
Allergic reactions such as facial swelling or swelling of other body parts such as hands or feet. There may be swelling of the mouth / throat and respiratory problems. If there is an allergic reaction to you, stop taking Daivobet and talk to your doctor immediately or go to the emergency room of the nearest hospital.
The treatment with the gel, the calcium levels increase in the blood or urine (usually when too much ointment has been used). Signs of increased calcium in blood are bone pain, constipation, loss of appetite, nausea and vomiting. This increase in value can be serious, and you should see your doctor immediately. However, the values return to normal once treatment is discontinued.
Less serious side effects
The following less serious side effects have also been reported during treatment with Daivobet:
Common side effects (in less than 1 in 10 people):
itching
Uncommon (affects less than 1 in 100):
Eye irritation
Burning sensation on the skin
Skin pain and skin irritation
Inflammation and swelling of the hair root (folliculitis)
Rash with inflammation of the skin (dermatitis)
Skin redness due to an expansion of small blood vessels (erythema)
Acne (pimples)
dry skin
skin rash
rash pustular
Less serious side effects that may occur under long-term use of betamethasone and their occurrence, you should inform your doctor or nurse as soon as possible are:
Thinning of the skin
Appearance of surface veins or stretch marks
Changes of hair growth
Rash with redness of the skin around the mouth (perioral dermatitis)
Rash with inflammation or swelling (allergic contact dermatitis)
Small white spots (Kolloidmilium)
Depigmentation (lightening of the skin)
Other less serious side effects that can occur with the use of calcipotriol
Photosensitivity reaction, which leads to rash
eczema
Please tell your doctor or pharmacist if any of you side effects gets serious, or you notice any side effects not listed in this leaflet.
If any of the side effects get serious or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.

How should it be stored?

Store drug out of reach of children.
Do not use X after the expiry date "EXP" stated on the carton after no longer apply. The expiry date refers to the last day of the month.
Do not refrigerate. Tube in the outer carton to protect from light.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist should be disposed of as the product when you no longer require it. These measures will help to protect the environment.

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