Ramipril 10 mg
28 tablets
Active substance: Ramipril
Ramipril: prevention of heart attack
Ramipril belongs to drug class of ACE inhibitors (angiotensin converting enzyme) and is used as an antihypertensive drug against hypertension. Ramipril is also used for the prevention of heart attack and other cardiac diseases, for example in heart failure. While it can be successfully treated with the drug ramipril hypertension, but it is not suitable due to the possible side effects for anyone. The dose of Ramipril is determined individually by the physician.
Effect of Ramipril
The blood pressure is constantly adjusted to the particular needs of the body. For stress or physical stress, the hormone angiotensin II is formed, which constricts blood vessels and increases blood pressure. In addition, angiotensin II stimulates the production of the hormone aldosterone also increase blood pressure. The active ingredient Ramilpril inhibits angiotensin-converting enzyme (ACE), a protein that is responsible for the formation of angiotensin II. Therefore, angiotensin II formed by Ramilpril less, which dilate the blood vessels and blood pressure drops. So also the heart is relieved, because it must pump blood against a lower resistance.
In addition, will be paid by the smaller amount of angiotensin II less aldosterone. This hormone makes the body that less water is excreted through the kidneys, causing blood volume and hence blood pressure rises. So ramipril has an additional antihypertensive effect by the decreased production of aldosterone. Since high blood pressure is a major risk factor for the development of atherosclerosis, ramipril can can thus protect them from serious complications such as stroke, angina pectoris, heart attack and other diseases of the cardiovascular system.
possible side effects
Ramipril may cause various side effects, which can vary depending on the dosage, duration, frequency of administration and dosage form of the drug. Common side effects of ramipril are:
blurred vision
Faintness or dizziness
Renal impairment
Bronchitis or dry cough
Digestive tract disorders and nausea
a headache
lack of concentration
Fatigue or increased need to sleep
Among the occasional side effects of ramipril include skin reactions such as hives and rashes or itching, wheezing, asthma attacks, sore throat and hoarseness. The concentration of hemoglobin may be reduced. Moreover, the blood composition may change. Occasionally heard a sudden drop in blood pressure to the side effects.
As rare side effects of ramipril among others fainting, rhinitis, reduction in kidney performance, vascular swelling and shock states are called. Patients should exclude possible risk factors before taking Ramipril and note the information leaflet.
Dosage and interaction
The dosage of ramipril must always be determined individually by the physician to the patient. This is especially true when other drugs are taken in addition, because an incorrect dosage of Ramipril combined with the use of certain medications severe interactions or side effects can cause. This is the case for example in certain forms of therapy of diabetes, lithium and certain drugs for gout, rheumatism, cardiac arrhythmias and cell growth disorders.
With the right dose of ramipril should also be noted that the drug in elderly people is stronger - as well as the effect of alcohol is greater, should be avoided on these while taking Ramipril. During pregnancy, ramipril is not to take because of the risk of serious birth defects and stillbirths is. If ramipril combined with another drug, such as with hydrochlorothiazide (HCT), the dosage is carefully coordinated.
Ramipril: Contraindications and alternatives
The active ingredient Ramipril should not be taken by children and adolescents under 18 years. Likewise, it is not suitable for people with narrowing of the renal arteries and the heart valves and severe kidney dysfunction and liver. Furthermore Ramipril must not be used in aldosteronism (excessive production of the hormone aldosterone). Because of the possible side effects of antihypertensive drugs is always specific to decide in each individual case, which means the most appropriate.
An alternative to ACE inhibitors are called AT1 antagonists. These drugs block a special "docking" (receptor) of angiotensin II, scored on the hormone the vasoconstrictor effect. Angiotensin-II is thus still formed, only the pressor effect remains off. It is less common to certain side effects such as cough or shortness of breath that can occur when taking ACE inhibitors. All drugs that act by blocking the AT1 receptors, have the extension "-sartan" the drug name, such as telmisartan.
In addition to ACE inhibitors and AT1 receptor antagonists, there are also drugs against hypertension, which act in a different way, such as the beta-blockers metoprolol and bisoprolol, or the calcium channel blocker amlodipine. Even drugs that are based on one of these agents, are not free of side effects and contraindications, and can just as ramipril interactions trigger by other means.
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